Pharmaceutical packaging process and the characteristics of aluminum foil printing – foil printing, pharmaceutical packaging, technology – the pharmaceutical industries
Its summary process: Aluminum Foil Unwinding Gravure drying drying Tu protective layer coating adhesion layer drying foil winding. The entire production process, the text of the gravure pattern of surface quality and the bonding layer to achieve the seal strength to protect the bonding layer and the temperature of dry and Coating Machine running speed, tension control, a process operation to tight grasp. Therefore, " Pharmaceutical Packaging Aluminum foil "State Standard Pharmaceutical aluminum foil on the surface quality of the printed word has a clear requirement for the protection layer, adhesive layer performance on physical and chemical indicators are to protect the medicinal PTP aluminum foil has good barrier properties, health security, and good sealing physical and mechanical properties. PTP aluminum foil printing coating in the production process to achieve the performance of these requirements, the application of raw materials still need to familiarize themselves with the performance and operation should pay attention to the following questions:
1. Aluminum foil and print master Ink Features
PTP aluminum foil used in the production of raw materials for industrial pure aluminum foil, generally require a thickness of 0.02mm, a tensile strength of 98kPa, rupture strength of 90kPa, the surface clean, smooth, no wrinkles, no indentation damage No fluorescent material into a film, wetting the surface tension of no less than 32. Pharmaceutical aluminum foil on the degree requirements for pinhole diameter of 0.1? 0.3mm pinhole more than 1 / m2. As the foil is penetrating the pinhole defects, drugs are oxygen, water vapor and light intrusion will reduce the efficacy or deterioration, so the pinhole is very strict degree requirements; other than the thickness of aluminum required if the deviation ( 10%), the bonding layer and protective layer will be the coating amount of impact required to cause the operator's attention.
Aluminum foil used in printing inks are currently divided into two categories: one for the Polyamide Class of ink. This ink printed on various materials have good adhesion, dispersion, luster, abrasion resistance, Solvent The release is good, soft, multi-used plastic film printing. Aluminum foil material used for the printing, the inks shown good performance can, and its heat-resistant aluminum foil can be printed to meet the requirements. Another is based on chlorine Ethylene Vinyl acetate copolymer Synthetic resin / Acrylic resin as the main component of aluminum foil special ink, the holding point is the brightly-colored, high concentration, and adhesion to aluminum foil particularly strong, with good transparency, but when used for intaglio printing, the solvent evaporation degree , PTP aluminum foil for the medicinal form is often caused by gravure roll printing dwell hole dry and ink deposition, resulting paste version of the phenomenon. So take the deposition of ink necessary to Frozen pretreatment, the method is to stir the ink deposition to Frozen or increasing temperature (water bath). If the ink is too long storage time, ink deposition occurs, resulting in ink resin solution over the upper and the lower Pigment More, the upper color light, the lower the color depth, it should stir before use.
2. Amount of ink solvent added to the appropriate
When the viscosity of the ink will need a lot of diluent should be added thinner edge stirring to evenly distributed throughout the thinner ink. Supplies meter measured at about 20? 30s between. Indoor temperature and humidity, affect the concentration of the ink, preferably ink concentration detector to determine the amount of added solvent, and in accordance with changes in temperature and humidity, measuring the time intervals of about the concentration of ink. Aluminum foil products used gravure printing, ink density is too low, will cause the printed word patterns Color Not bright, textured paste version of office phenomenon produced; ink density is too high, then the plan will occur at the chap, is not only a waste of ink, and could easily lead to the printing surface is not smooth, nor beautiful. In addition, also under the aluminum foil coating machine printing speed and printing dwell hole depth gravure roller to select the best ink.
3. Adhesive Should meet the requirements
PTP aluminum foil adhesive is coated on the inside of aluminum foil, aluminum foil and its role is to make medical PVC hard film can be firmly pressing together to make plastic hard drugs within the blister film separated from the outside world , to make medicines sealing purposes. Into medicines in the process of heat sealing, adhesive layer by pressing the role of activation, which with hard PVC plastic film firmly bonding as a whole, which requires bonding layer and the PVC resin should have good heat-sensitive and with the substrate compatibility.
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