develop more effective treatments for lung cancer and pleural mesothelioma
Global figures of mesothelioma patients are rising at an alarming rate and medical experts worldwide are now rushing to discover ways to treat the sickness. A study conducted in 2008 showed that there were approximately 174,300 mesothelioma cases from 56 countries that “use asbestos at substantial levels but report no cases of the disease.” Among 33 countries surveyed that did not report any mesothelioma cases, the researchers estimated a total of 38,900 deaths. Pleural mesothelioma is the most common type of mesothelioma and has been studied to a far greater degree than any of the other forms of the disease. However, it is difficult to diagnose pleural mesothelioma in its early stages because its symptoms often mimic the symptoms of other common illnesses, such as the flu, pneumonia or laryngitis. Benign pleural mesothelioma is often checked at the age of 50-60 years old, Malignant mesothelioma usually occurs in the right chest. Malignant pleural mesothelioma(MPM), originated from pleural mesothelium cell, is an fatal tumor with natual history of only about several months, has showed an increased morbidity recently.
The National Lung Cancer Partnership’s (NLCP) Young Investigator Research Grants were established “to support lung cancer researchers early in their careers and ignite their interest in the field.” The funding provided by these grants is critical to fostering innovative research and the promising doctors and scientists conducting it. Each year since 2005 the NLCP announces a new set of recipients, and 2011’s award winners will receive $100,000 total distributed over two years. Over the grants’ six-year existence, the NLCP has given out over $2.2 million to support lung cancer research.
One of this year’s grant recipients is Dr. Sunil Singhal, Thoracic Surgeon and Assistant Professor at the University of Pennsylvania in Philadelphia. Dr. Singhal’s work focuses on pleural diseases, including mesothelioma, a rare cancer of the protective lining of the lungs that can also affect the lining of the heart, chest and abdomen. His research is aimed at targeting immune-suppressing factors in order to develop more effective treatments for lung cancer and pleural mesothelioma.
As pleural mesothelioma is the most common form of mesothelioma, mesothelioma is often considered or spoken of as a form of lung cancer, but this is incorrect. Most patients do not have obvious symptoms. It was found when taken X-ray examination. About 50 percent pleura changes the cancer patient having malignant chest water that the pleura thins out the most common symptom of skin tumour is to breathe hard. Cough, chest tightness, shortness of breath, poor lung is an early symptom of pleural mesothelioma, 25 percent of clinical cases with fever, 25 percent of clinical cases with fever without infection to testify. Benign fibrous pleural mesothelioma is often accompanied by two new class of biological syndrome, Hypertrophic pulmonary osteoarthropathy and hypoglycemia. 20 percent of patients may have hypertrophic pulmonary osteoarthropathy, digital clubbing, joint pain, stiffness and ankle edema. Most patients with hypertrophic pulmonary osteoarthropathy, The tumor diameter> 7cm. Syndrome have been alleviated after surgery. 4 percent of benign mesothelioma have low blood sugar syndrome. it may be caused by the reasons cancer deplete lucose. Less common symptoms are Hemoptysis, chills, night sweats and weight loss, a small number of patients have pleural effusion. Using image study CT inspection is difficult to confirm the Benign pleural mesothelioma treatment.
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