Everything About Synarel
Synarel is a nasal solution which is commonly sprayed into the nasal mucosa of the patient. The drug will be absorbed directly into the circulation with this mode of administration. This mostly comes in 2 mg/ml solution. Before administering the drug by nostrils, set up the pump to get the actual dose prescribed by the physician. Every spray includes 200 ug of nafarelin and a bottle of this product will last up to 60 sprays.
For women, this drug is indicated to manage the symptoms of endometriosis like relief of pain and decreases the lesions in the endometrium. This is indicated only to women ages 18 years old and above.
The suggested dosage for endometriosis is 400ug and to be given via one nostril in the morning and the other nostril in the evening. It should start in the 2nd and 4th day of the period cycle. The dose may increase gradually up to 800 ug depending on your physician’s order. Treatment must last not greater than 6 months. No proof has been revealed relating to the drug’s efficacy and safety when utilized continuously. Bone density must be assessed before continuing the treatment to make sure that all values are in normal range.
There have been no reports of having a decreased absorption or effect when the patient has rhinitis or nasal congestion. Should there be a need for nasal decongestants, they must be given two hours once Synarel has been administered. Patients must try their hardest not to sneeze after or during administration of the drug to enhance its absorption.
There have been scientific reports that manifest drug allergic reaction such as chest throbbing, rash, urticaria and shortness of breath. The percentage of reports of experiencing palpitations, eye pain, chloasma, paresthesia and enlargement of breast in patients is less than one.Bone density levels may change and as evidenced by computed tomography, an 8.7% decrease is associated to drug usage later than six months.
Safety level of synarel has not been proven throughout pregnancy and this medication should be avoided. When using this drug, ovulation and mestruation will be halted. It is necessary to make use of contraceptive techniques to avoid contraception especially when the patient missed doses that are successive.
Menstrual flow is inhibited by the medicine to make itself effective. Should this happen, it is necessary to inform your doctor right away. Menstruation may result from noncompliance to drug therapy and dose of drug must then be increased to reach amenorrhea.
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