Modern traditional Chinese medicine on the treatment of cardiovascular disease t
Coronary heart disease is a serious threat to life or health of one of the major diseases. Hyperlipidemia, hypertension, obesity, smoking and diabetes, leading to coronary heart disease risk factors. The epidemiological study found that genetic factors, lifestyle, occupational and psychosocial factors, have with the pathogenesis of coronary heart disease. According to statistics, China's men, the incidence of coronary heart disease increased by 26.1% than in the past, women increased 19%. 2020, coronary heart disease deaths in the percentage of total global deaths will increase 50%, up to 25 million people / year. Such a high occurrence rate and high medical costs to governments and consumers, causing a heavy burden on the most urgent task is to find a safe and effective treatment of low-cost, patients can be long-term use and side effects of drugs.
Endothelial dysfunction, inflammation and oxidative stress and other factors in the occurrence and development of coronary heart disease plays an important role and therefore requires a view of these factors play a role both drugs. Modern Chinese Medicine CSDP with multi-component, multi-link, multi-target cardiovascular protective effect is based on traditional Chinese medicine theory and modern medicine combined technologies developed, and currently the only international traffic efficiency standards for innovation and modern traditional Chinese medicine pills doses . The drug from Salvia, 37, borneol composition, from the protection of myocardial protection of blood vessels, improving blood rheology characteristics of three play a multi-target pharmacological effects, and to better make up for the role of the Western unity. 1993 was approved as coronary heart disease, angina treatment market, because of its good clinical efficacy and safety has now become the prevention and treatment of angina pectoris, diabetes, vascular disease and other clinical first-line drugs are widely used by the clinical doctors and patients highly.
As the CSDP with the above-mentioned multi-target pharmacological effects, so in the treatment of various types of coronary heart disease, including stable or unstable angina, myocardial infarction, heart failure, silent myocardial ischemia as well as peri-operative intervention period of treatment and so on have significant effect. Coronary heart disease is a traditional Chinese medicine, "Chest" category, the mechanism of blood stasis Xinmaitong, Bizu unreasonable, not pain General. CSDP is a water-soluble Danshensu, 37 saponins as the main component of a pure Chinese medicine, with Huoxuetongmai, stasis analgesic effect, can dissipate blood stasis, qi and blood and play a tune over the treatment of thoracolumbar Bi heartache to the role of the size of the vascular complications of diabetes, including diabetic retinopathy, diabetic nephropathy, diabetic peripheral neuropathy, also have very good results.
CSDP treatment of stable angina clinical efficacy has been affirmed, and as the extension of treatment time, the clinical effect is more significant. Recent studies suggest that arterial intima-media thickness (IMT) and cardiovascular diseases is closely related to carotid IMT for each additional 0.1mm, the incidence of myocardial infarction increased by 11%. In the one led by the Ministry of Health Beijing Hospital, carried out by multi-center, large sample of clinical trials (National "15" research fund projects), "macrovascular complications in type 2 diabetes, interventions and control model", the prompt CSDP the treatment group could be significantly delayed by adjusting the HDL2C metabolism MT thickening of carotid artery, thereby reducing the incidence of major vascular disease, for early atherosclerosis has a protective effect, can reduce the incidence of cardiovascular and cerebrovascular diseases, but also safe and reliable, treatment 2 year period found no adverse reactions.
CSDP microvascular complications of diabetes is also a very good effect, such as diabetic retinopathy using CSDP after treatment than before treatment in patients with markedly improved visual acuity, retinal hemorrhage, tumor microvessel number and gray value than the treatment of vision the former decreased significantly. The diabetic peripheral neuropathy in patients with CSDP treatment, can alleviate the symptoms, exercise, sensory nerve conduction velocity increased.
CSDP is a traditional Chinese medicine theory, under the guidance of refined through modern technology made the compound traditional Chinese medicine preparation. Role of the target numerous curative effect, after 10 years of a large sample of clinical applications, no serious adverse reactions in clinical use of safe and reliable, long-term use can now become the treatment of cardiovascular and cerebrovascular and related diseases, the preferred medication. As has been by the U.S. FDA new drug application of modern clinical medicine, is currently being planned in the United States as a treatment for coronary heart disease, angina drug market, as proprietary Chinese medicines to the world has taken a crucial step forward.
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