Nano Spray Dryer
Functional principle
The functional principle is basically the same as with normal spray dryers. There are just different technologies that are used to do similar things.
The drying gas enters the system via the heater. A new kind of heater system allows for laminar air flow. The spray head sprays the fine droplets with a narrow size distribution into the drying chamber. The droplets dry and become solid particles. The solid particles are separated in the electrostatic particle collector. The exhaust gas is filtered and sent to a fume hood or the environment. The inlet temperature is controlled by a temperature sensor.
Applications
Scanning electron micrograph of gelatine particles spray dryed with a nano spray dryer
Scanning electron micrograph of grisofulvin particles spray dryed with a nano spray dryer
Pharmaceuticals: This technique is widely used in the pharma market. Because of the small sample amounts and the high yields it is ideal for spray drying expensive substances in basic research. The following list shows examples of what is possible:
Inhalable drugs for Dry Powder Inhalers (DPI)
Nano- and microencapsulation of liposomes
Stabilization of heat-sensitive vaccines, insulin, growth hormones
Encapsulation of nanoparticle drugs for high bioavailability
Nanocapsules of biodegradable polymers (lactides, glycolides)
Porous drug carriers for nanoparticle suspensions
Excipients for controlled drug release studies: trehalose, mannitol, lactose, HPMC, PVA, chitosan, dextrine, PLGA, starch, gelatin
Materials science: This new technique offers new prospects in materials science, specially in the nanomaterial field. Now it is possible to spray dry fine particles. The following list shows examples of what is possible:
Fine metal particles for novel catalysts
Fine magnetic powders
Carbon nanotubes as additives
High performance ceramics with novel structures and high specific surface area
Titanium oxide particles
Nanoparticle suspensions for agglomeration
Silicon oxide nanoparticle agglomerates
Finest pigments for paints and coatings
Food: Also in the field of food science this technology offers new possibilities. Especially in the currently vibrant field of functional food, the following list shows examples of what is possible:
Nano food Functional additives
Encapsulation of fruit aromas, flavours, or perfumes
Spray drying of fine powder aromas for pet food
Encapsulation of fish oil for smell protection
Vitamins, other food additives, etc.
Spray head
One of the three new technologies that makes “nano” spray drying possible is the spray head. A piezoelectric system precisely vibrates a fine mesh. Vibration produces fine droplets with a narrow size distribution.
Vibrating mesh of a nano spray dryer spray head
Size distribution of the droplets produced by the spray head
Heating system
In the field of “nano” spray drying a new heating system is used to provide the drying gas to produce the particles. The gas flow in the system is laminar and not turbulent as in common spray drying. The advantage of a laminar flow is that the particles fall straight down from the spray head and do not stick to the glass wall.
The laminar flow is produced by pressing the air through a porous metal foam.
Electrostatic particle collector
To collect the very fine particles a new technology is used in the field of “nano” spray drying. The reason is that common cyclone technology depends on the particle mass; particles smaller than 2 m can be separated and instead exit the system along with the exhaust gas.
The electrostatic particle collector charges the dry particles’ surface and deflects them with an electrical field. To produce the electrical field, a high voltage (16 kV) is applied to a round collector tube. The electrical field builds up between the inner wall of the collector tube and the tips of a grounded star electrode. To have a low level of energy in the system the current is very low.
After getting deflected the particles stay at the inner wall of the particle collector tube and are completely uncharged. This separation method works fine for all kinds of materials.
The efficiency of the electrostatic particle collector is very high: 99% of all particles that enter the system are collected.
Electrostatic particle collector
Functional principle of an electrostatic particle collector
Categories: Scientific method | Scientific equipment
I am a professional writer from China Hardware Suppliers, which contains a great deal of information about samosa machines , automatic meat slicer, welcome to visit!
Processing your request, Please wait....
