Indication of Rebeprazole with Demperidone
Rabeprazole is prescribed to treat conditions where the stomach produces too much acid, including ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. Rabeprazole is prescribed in combination with other prescriptions to eliminate H. pylori, a bacteria that causes ulcers. Rabeprazole is in a class of prescriptions called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.Rabeprazole prevents the production of acid in the stomach. It reduces symptoms and prevents injury to the esophagus or stomach in patients with gastroesophageal reflux disease (GERD) or ulcers. Rabeprazole is also useful in conditions that produce too much stomach acid such as Zollinger-Ellison syndrome. Rabeprazole may also be used with antibiotics to get rid of bacteria that are associated with some ulcers. Rabeprazole is a selective and irreversible proton pump inhibitor, suppresses gastric acid secretion by specific inhibition of the H+, K+ -ATPase enzyme system which is found at the secretory surface of parietal cells. It inhibits the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen.
Short-term treatment in healing and symptomatic relief of duodenal ulcers and erosive or ulcerative gastroesophageal reflux disease (GERD); maintaining healing and reducing relapse rates of heartburn symptoms in patients with GERD; treatment of daytime and nighttime heartburn and other symptoms associated with GERD; long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome and in combination with amoxicillin and clarithromycin to eradicate Helicobacter pylori.
* Gastric ulcer(GU)
* Peptic ulcer disease (PUD)
* Maintenance of healing of erosive or ulcerative GERD
* Healing of erosive and ulcerative GERD
* Healing of duodenal ulcers.
* Treatment of symptomatic GERD
* Treatment of pathological hypersecretory conditions (Zollinger-Ellison syndrome)
* Helicobacter pylori eradication to reduce risk of duodenal ulcer recurrence
Rabeprazole is in a group of drugs called proton pump inhibitors. Rabeprazole decreases the amount of acid produced in the stomach.Rabeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Rabeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).Rabeprazole may also be given with an antibiotic to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori).Rabeprazole is not for immediate relief of heartburn symptoms.Rabeprazole belongs to the class of medications known as proton pump inhibitors (PPIs) and it works by reducing the production of acid in the stomach. Rabeprazole is used to treat and maintain healing of gastroesophageal reflux disease in adults. It is also used for short-term treatment in the healing and relief of symptoms associated with duodenal ulcers.
Rabeprazole is used to treat gastroesophageal reflux disease (GERD), severe erosive esophagitis, poorly responsive systemic GERD, pathologic hypersecretory conditions such as Zollinger-Ellison syndrome, systemic mastocytosis, multiple endocrine adenomas, and active duodenal ulcers.Rabeprazole is the fourth proton pump inhibitor to be approved in Australia. The other members of the class are omeprazole, lansoprazole and pantoprazole. Rabeprazole has been compared with omeprazole for each of its approved indications. Although many patients with duodenal ulcer will require treatment for Helicobacterpylori, the proton pumpinhibitors can also be effective. After four weeks of treatment rabeprazole and omeprazole had healed more than 90% of the patients. Similar results were found after treating patients with gastric ulcers for six weeks, and patients with erosive or ulcerative gastro-oesophageal reflux disease for eight weeks. If patients with gastro-oesophageal reflux take rabeprazole or omeprazole for a year
only about 5% will have a relapse.
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