Scientists map out lung cancer and skin cancer complete genome – gene – the phar
British scientists announced that the first time they successfully draw Lung Cancer And the complete genome of skin cancer, the British Academy of Medical Sciences Dean John? Bell said this in the last decade Cancer Research and treatment of "change" of the progress of research published in the 17th issue of "Nature" magazine.
Leader of the study, the British leader of the Cancer Genome Project, Mike? Stratton that draw a complete map of the cancer gene means that doctors can be found in earlier human cancer cells, the patient accordingly prevention; and only require a simple blood test, and then under different circumstances of each individual to develop a "personalized" treatment plan; also help scientists develop as soon as possible for a particular gene mutation Anti-cancer drugs Material.
Scientists draw out the two latest map in the record of human cells, thousands of gene mutation, it is these mutations lead to cell-based, resulting in cancer.
Charity Cancer Research UK will be responsible for human Ha Paer? Kumar said the next step will be from thousands of genetic variation in the real guide to find out which variation Cancer Cell formation and proliferation, which is sporadic gene mutation, so that we better find a way to carry out corrective and preventive. Draw a complete gene map of cancer cells also contribute to healthy populations MoT test blood samples to test out whether they could have produced DNA lesions.
The experts pointed out that despite the impact of environmental factors on cancer, great, but fundamentally speaking, cancer is a DNA defect disease. DNA defects can cause gene mutations (some of the Carcinogens Induced), so that some cells began to divide uncontrollably, and then spread in the body. More and more studies show that cancer is not a single disease, each cancer include a large number of different types of mutations caused by the different sub-categories, need to symptomatic treatment, respectively.
Present these two maps is the Association for International Cancer Genome "cancer genome project," the first results. International Cancer Genome Association April 29, 2008 was established, it is set in China, the United States, Britain and other 10 members of the force of scientists, drawing a complete map of human cancer genes. The organization plans to invest 1 billion U.S. dollars, with 10 years of detailed study of 50 kinds of cancer can lead to variations in genes, to map out the full map of these genes.
The association plans to study each type of cancer, the extraction of 500 patients with this type of cancer in which cancer cells and the genes were sequenced, and then the results with healthy cells, genes coding for comparison to determine which variation of the real gene lead to cancer formation and proliferation, and which genes are occasional variations.
Human cancer genome mapping, if successful, is expected to open up a new era of individualized treatment of cancer. Doctors will be able to know exactly when patients with tumor growth and spread of specific genetic factors, so that individuals choose a specific cancer treatment easier. The program also helps to design the genetic vulnerability to cancer drugs that target.
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