HeartBurn No More Review >> Are you anxious? Blame your neuropsin
Only a small proportion of people who suffer a traumatic event develops after an anxiety disorder. The key to this disparity may be a protein called neuropsin. In a situation of stress, the emotional center of the brain, the amygdala secretes this molecule and thus trigger a phenomenon known as anxiety.
The discovery of this signaling pathway in the brain Scientists have made the University of Leicester (UK), Institute of Science and Technology, Nara (Japan) and the Institute of Pharmacology, Krakow (Poland). Could be useful for developing new treatments or prevention methods such problems.
“The anxiety-related disorders affect a large percentage of the population [about 30% over lifetime] and generate great personal impact, social and economic development,” says Robert Pawlak, director of the British team. “It was known that There are certain people who are more susceptible to the effects of stress, But the reasons were not clear. ”
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The authors of the study, published in the journal Nature’, Began to investigate the molecular basis that trigger anxiety. They found that the amygdala, in a stressful situation secretes neuropsin, a protein that triggers a series of reactions that culminate in gene activation Fkbp5, “involved in the development of anxiety, depression and posttraumatic stress disorder (PTSD),” said Article.
With this information on the table, created neuropsin-deficient mice and found that this signaling pathway was activated and did not develop anxiety when they were subjected to a stressful situation.
“When proteins made by the amygdala were blocked, either pharmacologically or by gene therapy, the mice did not exhibit these traits. The behavioral consequences of stress were not present, “says Pawlak.” Our conclusion is that the action neuropsin may determine the sensitivity to stress“.
Although the study has been done in rodents, the authors are optimistic because all the molecules involved in this reaction are also present in the human brain. This opens the door to prevention and treatment of psychiatric disorders such as depression or PTSD,
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