Grow taller 4 idiots review – The “shielding” of bacteria to antibiotics, uncovered
The team began the study of a protein produced by a “superbug” after several years different genetic studies revealed that the “Staphylococcus sciuri ‘(a non-human bacterial pathogen) had developed a new gene called’ Cf ‘. As noted, the protein created by this gene plays a key role in one of the mechanisms of the bacteria to become resistant to antibiotics.
Successive studies showed that the same gene was crossed with a strain of Staphylococcus aureus, a bacterium that is part of the flora of the nostrils and the skin and causes some of the most common bacterial resistance.
Because this gene is often found within a component of DNA, can easily switch to other non-human pathogenic species of bacteria that infect other humans.
“The gene, which has been found in strains of Staphylococcus aureus in the United States, Mexico, Brazil, Spain, Italy and Ireland, can cause bacteria to become resistant to seven types of antibiotics,
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This shows that these bacteria have “a distinct evolutionary advantage” because of this gene, although so far not had an image “clear” about what was happening at the molecular level.
Methylation of proteins
To solve the mystery of how bacteria chemical “fun” to many antibiotics, team analyzed the methylation process of the protein ‘Cf’, by which enzymes add a small molecular label in nucleotides (structural units of RNA and DNA).
When this tag is added by a molecular protein called ‘RlmN’, it promotes the synthesis of proteins that bacteria need to survive.
Now, however, have observed that the protein ‘Cf’ performs a function identical to the protein ‘RlmN’, adding the molecular tag in a different location on the same nucleotide, which is “a really new chemical mechanism in methylation.”
explains, the next step will be to use this information to design new compounds that act in conjunction with traditional antibiotics. “We know the specific mechanism by which bacterial cells avoid some antibiotics, then we can start thinking about how to interrupt the process so that the traditional antibiotics do their job,
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