First to prevent the prevalence of H5N1 pre-pandemic vaccine approved – the flu,
GSK's Prepandrix? H5N1 pre-pandemic vaccine was first approved in Europe
2008 5 20 GlaxoSmithKline (GSK) announced today that the European Commission has given the company GlaxoSmithKline Biologicals H5N1 adjuvanted pre-pandemic vaccine Prepandrix issued a listing of authorization that all 27 EU countries in full force and effect.
GSK is the first pre-pandemic vaccines to obtain authorization of the company in Europe, so let European governments officially announced in advance or when an influenza pandemic protect its people.
"This vaccine marks all over the world against an influenza pandemic a significant improvement. This is a pre-pandemic vaccine GSK research led scientists to obtain evidence of success, it fulfilled our commitment to do everything in our efforts to help prevent a pandemic disaster hazards, and to reverse the harm to public health crises do our reach. "GSK chief executive Jean-PierreGarnier said.
World Health Organization (WHO) that the vaccine is the prevention of influenza during a pandemic and reduce the pandemic on the health hazards of the most important interventions.
"Pre-pandemic vaccines" to protect more effectively
There are two types of vaccine are now open to the government?? Pandemic influenza vaccines and pandemic influenza before the vaccine.
Pandemic influenza vaccine is declared influenza pandemic, the use of a specific pandemic strain produced immediately. However, the relatively long production time required for such a pandemic vaccine can only be 4-6 months after the supply is used, which for the first round of the harm caused by a pandemic, it seems too late.
Pandemic influenza vaccine before the pandemic occurs in advance of production. This vaccine is now found under may lead to a pandemic Avian flu H5N1 virus production, may be popular for the H5N1 strain of the virus induced protective immune response. Therefore, pre-pandemic vaccine in pandemic preparedness planning stage play an important role. Experts believe that in the pre-pandemic or pandemic reserve this pre-pandemic vaccine is to protect the public the most effective strategy.
"Pre-pandemic influenza vaccine is the deal with the current H5N1 pandemic threat of an important strategy," GSK Biologicals president and general manager of JeanStéphenne said, "GSK welcomes the EU approved Prepandrix, and will continue to work actively and the Government Cooperation , To prepare for the pandemic, the potential for a pandemic disaster to provide effective protection. "
Indications between the ages of 18-60 years old
Prepandrix formula to a new proprietary adjuvant system, its design goal is to give low doses of antigen in the case of obtaining a high level of immune response, but also for broad-spectrum of the H5N1 strain of the virus have a lasting effect of active prevention. Currently, the EU mandated the vaccine is indicated between the ages of 18-60 years, using the WHO recommended the Vietnamese strain of the virus, tests proved that the use of such antigen vaccine strain against three specific strains of H5N1 virus variants , that is, for now in Asia, Europe and Africa epidemic H5N1 virus mutates.
There is the possibility of an influenza pandemic H5N1
H5N1 influenza (commonly known as bird flu) infection in birds and humans may lead to serious illness. So far, WHO has reported 382 human cases of H5N1 infection in these cases from 14 countries, resulting in 241 deaths. Public health experts fear the virus will evolve into a very easily spread virus between humans and trigger a worldwide influenza pandemic.
Pandemic is virtually no immunity to the virus of human infection worldwide outbreak. H5N1 is one such flu virus strain.
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