Domestic non-destructive oxygen parameter detector made important progress in cl

Biomedical Engineering from the Tsinghua University School of Medicine, the research team developed the first in China after a long developed with independent intellectual property rights Nondestructive near-infrared parameters of tissue oxygenation Detector Recent clinical research stage in the stage of important results obtained. Studies show that the instrument nearly infrared spectroscopy (NIRS) technology for strong scattering of human tissue, can realize the absolute amount of tissue oxygen saturation, hemoglobin concentration in tissue volume of non-invasive, continuous, real-time detection, making China second only to Japan, the United States production of such products after the third countries.

Parameters of tissue oxygenation is a new indicator of the types of oxygen in capillary blood parameters (including blood concentrations of total hemoglobin, oxygen saturation, etc.) weighted average, the clinical application potential.

According to Tsinghua University School of Medicine Department of Biomedical Engineering Professor Ding Haishu introduction, body tissue (such as the cerebral cortex, muscle tissue free flap, etc.) rely on a rich micro-veins, arterioles and capillaries to achieve peripheral microcirculation . As the micro-blood flow rate slower than the micro-blood, so the parameters of tissue oxygenation in the former dominant. Organization a long time can cause functional hypoxia injury and organic necrosis, or even life-threatening. Therefore, the non-invasive, continuous, real-time monitoring of human tissue oxygenation status, and to take appropriate effective measures to prevent hypoxia, have important clinical significance. However, after oxygen-made testing equipment is still in the blank parameters.

Present, primarily through two methods of clinical detection of blood oxygen parameters: First, invasive blood gas analysis, that is, a large blood vessel taken from human blood, using blood gas analyzer. This method can not only get the blood oxygen content, but also get the blood electrolyte levels and biochemical information. Second, non-invasive detection of arterial oxygen saturation. Method is to oximeter sensors in the fingertips folder (or earlobe). Detection principle is based on where arterial blood pulse, extracted by the light emitted through decay to calculate the exchange component.

Professor Ding Haishu analysis, blood gas analysis although certain large blood vessels can be detected in blood oxygen saturation, to a certain extent, indirectly reflect tissue oxygenation status, but it is invasive means, not real-time, continuous monitoring; finger pulse oxygen test although non-invasive, but given that arterial oxygen saturation, generally can not reflect local tissue oxygenation status of the human body. Independently developed by China near-infrared non-destructive testing instrument parameters of tissue oxygenation can be given a specific micro-vascular tissue Department of oxygen conditions and with non-invasive, continuous monitoring of the advantages, therefore irreplaceable characteristics and advantages. The instrument is particularly suited for monitoring brain, skin, muscle and other local tissue blood flow and heart beat in the implementation of weak or even during cardiopulmonary bypass can work.

Parameters of tissue oxygenation is a useful new indicator of research topics may be more extensive. According to Professor Ding Haishu introduced in the oxygen parameter prototype developed, the research team selected a number of areas of clinical application and has made important progress: guidance from the Peking University First Hospital, China also carried out in 9 hospitals neonatal cerebral hypoxia large sample of ischemia, has been the standard value and a number of detection rules; with the Beijing Sport University Cooperation Study of oxygen metabolism in skeletal muscle has been assessed to obtain characteristic parameters; Dental Hospital, in cooperation with Beijing after the blood supply, flap monitoring; and Zhen Hospital, Beijing cooperation for cerebral protection during cardiac surgery. Other studies also include trends in adult cerebral ischemia in the early detection, anti-cancer drugs on the arterial blood supply of anti-hypoxic effect of the quantitative assessment of drugs, TRAM flap breast reconstruction surgery of choice, hypoxia (such as altitude) training effect evaluation, bilateral blood flow in patients with lumbar comparative studies.

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